ADVANCED PRICING TECHNIQUES Assignment Example | Topics and Well Written Essays - 250 words

ADVANCED PRICING TECHNIQUES - Assignment ExampleUS has an absolute advantage in ______________Chemicals____________ ( change state, chemicals, both apparel and chemicals, neither apparel nor chemicals).e.China has a comparative advantage in ________ both apparel and chemicals __________________ (apparel, chemicals, both apparel and chemicals, neither apparel nor chemicals). US has a comparative advantage in __________ neither apparel nor chemicals ________________ (apparel, chemicals, both apparel and chemicals, neither apparel nor chemicals).g.Compared to the initial optimal product combinations D and S, world output of chemicals is ________smaller________ (smaller, greater) by __18___ tons of chemicals and world output of apparel is ________greater________ (smaller, greater) by __28___ 1000 units of apparel.i.Based on the actual terms of trade in previous part of this question, US can now choose four 1000 units of apparel and ___1.5___ tons of chemicals and China can now choose si xer tons of chemicals and ___1.5___ 1000 units of apparel. Specialization and trade between the two nations has ______decreased________ (decreased, increased) the standard of living in US and has ________Increased______ (decreased, increased) the standard of living in

Proto-oncogene in prevention of cancer is my focus biochemistry Research Proposal

Proto-oncogene in prevention of cancer is my focus biochemistry - Research Proposal ExampleA regeneration at the proto-oncogenes results in the production of oncogenes that can cause the hereditary cancer syndrome. The mutation causes the alteration in the oncogene protein expression level and a change in the structure of the protein. If more than one oncogene is activated in the mobile phone, then the abnormal cancerous cellular telephone production occurs. Proto-oncogenes are activated by three mechanisms. They are point mutations, chromosomal translocations, insert mutations, protein-protein interactions and gene amplification. Ras protein is an important product of proto-onco gene. Ras is one of the most important switches in the cell signaling pathway.1 There are three Ras proteins in the mammals. If any mutation occurs in the ras protein then it will result in the cell proliferation stimulation and finally apoptosis will be inhibited. Thus tumor cells will be produced. Th e ras mutation is one of the reasons for 30% of all the valet cancer. H-ras, K-ras and N-ras mutations are be in almost all types of cancers. 1 Hence research in this field is much essential because of its importance in the carcinogenesis. anti cancer therapy for the Ras protein is preferred in order to reduce and cure the cancer. Can anticancer therapy cure cancer? Scientific Background McGlynn et al. (2009) looked up at the Ras/Raf-1/mitogen-activated protein kinase (MAPK) pathway and looked its quality in the development and proliferation of cancer.2 They used chemotherapy for the treatment of cancer. Tamoxifen was used for the treatment. They looked up to know whether MAPK pathway has any major role in the carcinogenesis or not? Tamoxifen is an estrogen antagonist and the study was performed to check whether they can act as a target for the estrogen cancer therapy or not? For these two questions Mcglynn et al have found that Ras pathway responds very less for tamoxifen and go od for chemotherapy. pRaf(ser338) is found to be the best marker with great effect for the targeted estrogen therapy. A combination of chemotherapy along with tamoxifen is required for the therapy. Further new researches are going on to site comminuted and simple molecules for the treatment of cancer. The signaling pathway molecules are considered to play a very important role in the cancer therapy. Farnesyltransferase (FTI) is an important inhibitor of small molecules. This enzyme is very important for the prenylation of Ras. Tipifarnib is one of the FTI that are used for the treatment of cancer. Here the role of tipifarnib in the Ras signaling pathway was analysed and the growth arrest and cell death related to the ERK and MAPK pathways were looked upon.3 Tipifarnib treatment was found to inhibit and sensitize the ERK and MAPK pathways. They have concluded that geranyl geranylated N-Ras or K-Ras Bare sensititve to tipifarnib and interact in a diametrical manner in the downstre am signal processing at the osteosarcoma cells. This helps to maintain the balance between the cell death and proliferation. 3 The metasatasis ability of the cells is found to be enhanced by the ras activity. The poor understanding of the Ras protein is a big draw back in the treatment of cancer. Here Varghese et al (2002) have looked up to know whether macroscopic metastases are being affected by Ras or not. They have used Green fluorescent protein-transfected NIH 3T3 and T24 H-ras-transformed (PAP2) fibroblasts in the mouse and looked for the

To Whom It May Concern Essay Example | Topics and Well Written Essays - 1750 words

To Whom It May Concern - Es learn ExampleIn a further to hide something Quick, Lucy Dont fill your blouse with missing cherries from the confection assembly line Stuff it, girlAlthough farce theatre has its origins in France, many would argue that it has been perfected by the English. Few would disagree that whilst naming influential forces within the world of farce theatre, it would be appropriate to include many works produced by British entertainers, oddly the members of Monty Python. Today, however, it is entirely possible that the bulk of our comedic diet, as Americans, is made up of farce, usually in the form of sitcoms, but also prevalent upon the stage. We seem to have a taste for the outrageous, hysterical episodes of characters caught in ridiculous circumstances. A prime example of farce upon the stage can be seen in Michael Frayns play, Noises Off.Noises Off, is a play whose staple fiber plot entails the misadventures of a struggling, low-budget theatre troupe attempti ng to pull together and make their performance of Nothing On, a success. In the first act, we see the confused cast members acting out what happens when a wealthy couple trying to avoid the taxman return home from overseas, but without letting anyone-especially the IRS-know. Meanwhile, their home, which is up for let, is being-shall we say explored-by others who dont suspect anyone of being home. This comedy of errors, so cleverly done and well-thought out, makes us forget for a moment that we are watching a play within a play. However, we are soon reminded that the actors on stage are playing actors. It is during this opening act that we see the various relationships between the cast members, who are potty with whom, and exactly where all those pformer(a)s of sardines go.In the coterminous act, we see another performance of Nothing On, only this time with completely different chemistry between the cast members. What began, in act one, as a rather jumbled, stressed, but good-natu red set of people, several of whom were involved romantically, has devolved into a group with growing suspicion and hurt feelings due to a series of misunderstandings.By act three, the confusion has led to outright hostility between the majority of the cast, and we are left where we began with a plateful of sardines. Within the next few pages, please take a look at set design for Noises Off. Act I We need to start with the characters. Since this play within a play happens solely within the theatre during rehearsal and show time, the characters will always be dressed like their characters.Dotty Otley A woman in her early forties, dressed like a housekeeper, with a mid-calf length dress in a drab color, a full-length apron, sensible shoes. Her hair must be pulled back.Flavia Brent A woman in her late thirties, dressed like a yuppie. Tasteful neutral clothes, jewelry.Roger Tramplemain A man in his late thirties, dressed in a smart causa. Burglar A man in his early sixties, gray hair, wearing a pitch blackness turtleneck, black leggings, black shoes and black gloves, along with a black ski mask, pulled away from his face.Vicki A pretty, dark-haired woman in her early twenties, wearing a suit appropriate for working in an office.Philip Brent A man in his la

Design and Build Essay Example | Topics and Well Written Essays - 250 words

Design and Build - Essay Exampleostly cultural hereditary pattern issues and sustainability always come into conflict with the existingities of economical survival for example cutting down of trees has prevailing pragmatic consideration. Saving trees can make a connection to escape severe poverty which comes as a result of deforestation. When facing different parameters the solution would be to save trees but for the pedagogical process, deliberation and assignment with complex issues at work there were more important things than the specific outcome (Frances, 145).For decades architectural educators and practitioners have observed that there an increasing alarm in decreased significance of the architectural work. It is more acute on diminishing architectures power in cultural and social changes. Irreverence of our work is at critical juncture and therefore schools of architecture must act quickly to the complex, divergent and varied social demands.The basic initiative believes that community alarming economic predicament, traditional knowledge and community based practices offers a chance of chances of negotiating a better life. The process of undertaking throw and build practices in a community based culturally and socially helps a student to understand how architecture operates and bring about change to the community (Frances, 210).In this students do real projects designing and in real communities which has the benefit of collaborative synthetic learning experiences from real building and working in poor community. Students participate in design and build as a piece of architecture and on completing they compelled to show their experience by evaluating their design in context of their real

World hotels Literature review Example | Topics and Well Written Essays - 750 words

World hotels - Literature review ExampleThe location fits the expensive pockets and those who are sourced from selected categories. It is however satisfactory when in chore with other hotels and casinos (Aaker, 1997).This Resort is situated in a city space therefore, the aspect of country or outdoorsy has been violated in the five elements of brand personality. The excitement is not exactly felt by its look as it is presented as more formal than exciting here. It is, however, sophisticated and captures the business class. Grand Macau is sincere in its setting as well as competent among others (Aaker, 1997).The Monte Carlo, Singapore boasts of a classic attraction and is located in a large open space. Ruggedness for its outdoorsy and tough look definitely reigns here. It gives a feeling of excitement and sophistication. However, it is not sincere, and no element of rarify to earth is factored here. It is somehow intimidating (Aaker,

Applying Rhetorical Theory with Communications Essay

Applying Rhetorical Theory with Communications - Essay ExampleAristotle identified three forms of appeal ethos, pathos and logos (Henry 16). These elements have been applied by many famous orators including the President Obama, the current USA president during his inaugural oral communication. This paper will focus on the use of Aristotles elements in developing a speech communication to address employment leaders on the importance of allowing their employees time off so as to participate in fund donation.Aristotles Classical theory on speech is based on five rhetorical canons. These include the use of invention, disposition, style, delivery and memory. Invention involves the selection of a exemplar that will help in the attaining the purpose for the speech. Disposition, on the other hand dictates the arrangement of a speech so as to achieve the purpose of the speech. The speech will include the following a brief history, epidemiological fact and the procedure of blood donation . It will also explain the benefits to the business for allowing their employees to go for blood donation.Style involves the use of creativity in expressing ones ideas. This involves the use of details, figures of speech and creative analogies during the speech. The speech will include epidemiological facts on how many businesses have benefited from tolerant their employees time-off for blood donations. These facts will be represented in graphs and charts relating increased profits with participation in blood donation. Memory involves the use of devices that will ensure that the business leaders do not forget the details in the speech. This will include the use of picture representations and repetition of the important points. Delivery focuses on how the speech will be delivered.Aristotle viewed the use of rhetoric as a means of persuasion without the use of torture unlike the ancient Greek practices. He put on that a great orator is able to consider his audience and provide proof for his argument. This speech is directed towards business leaders. It is

Performance management or performance evaluation Essay Example for Free

Performance management or performance evaluation EssayThe basic aim of performance management is to create an environment for the employees where they can snip at their best. It begins when a particular job is defined whereas it ends when the employee quits from the organization and performance management basically serves as a replacement of the traditional assessment system. There are certain advantages of performance management and the most important one is the goal of developing clear job descriptions for the employees that can be soft comprehended by them. The second advantage is that it helps the employer to hire the best candidates for the job that suits them and at the same time, performance management helps them to negotiate with the employees on various issues. When the employee is at long last hired, he can be provided with necessary training followed by the feedback of the coach that enable organization to develop sessions in which issues regarding performance dev eloping can be discussed and according to the results of the performance of the employees, the remuneration package can be designed.Moreover, performance management also provides various career opportunities for the employees and can also provide helper when steering exit interviews to know why the employees choose to leave the organization. The concept of annual performance is a bit different from that of performance management. When managing other people, the manager has to conduct performance appraisals in order to know how the employees are performing and this can help motivate the employees to work well in future.Annual performance is basically done to evaluate the performance of the employee and to know how well they have worked throughout the year and the contributions that they have made for the progress of the organization. It not only helps in the development of the staff but it also improves the communication between the staff and the managers, however annual performanc e has some disadvantages as well.When conducting performance appraisals, employees might ask for feedbacks from their friends in the organization who are more likely to give positive feedbacks and may avoid any negative comments of the employee. Moreover, when conducting appraisals the companies often send evaluations to the raters without telling them how to accurately do the appraisal and without advance notice. (Leat, 2001). Reference Leat,M. (2001). Exploring Employee Relations. Butterworth-Heinemann.